Risk even higher with psychiatric comorbidity, particularly when diagnosed at young age

Experiencing overdose loss linked to greater odds of viewing addiction as an extremely or very important policy issue

Declines not spread equally everywhere -- some states experienced another year of increases of fatal ODs

Disparities observed for nearly all leading causes of injury and disease associated with recent increases in youth mortality rates

Not to the extent of the United States, but midlife deaths are worsening in the United Kingdom as well

Particularly large increases were seen for American Indian or Alaska Native and Black individuals

Dose-response association seen with higher risk for each additional delirium episode

Increased risk seen for premature death from noninjury, unintentional injury, and intentional injury

Findings show similarly increased risk in men and women based on pooled odds ratio from longitudinal studies

Significantly lower rates seen for all-cause mortality and unnatural-cause mortality, but not natural-cause mortality