<p>In response to the incident, Hartford officials pledged to ensure that all city schools are stocked with naloxone</p>

<p>However, wide variation seen in provider uptake</p>

<p>For patients with opioid use disorder taking buprenorphine-naloxone, it is deemed appropriate to continue three times-daily dosing</p>

<p>Greatest decline in MME volume per capita seen among persons aged 46 to 55 years and in metropolitan counties</p>

<p>Likelihood of developing POU increased for those with history of drug abuse, preoperative muscle relaxant or benzodiazepine use</p>

<p>Settlement was reached in thousands of lawsuits against OxyContin maker Purdue Pharma for its role in opioid epidemic</p>

<p>Figure is almost 30 percent higher than the previous year, when 78,000 overdose deaths were reported</p>

<p>It is not clear how the decision will affect similar cases nationwide, since most public nuisance laws are state-specific</p>

<p>In a tentative ruling, plaintiffs' claims that companies used deceptive marketing to increase unnecessary prescriptions was rejected</p>

<p>Group-based CBT intervention produced modest, but sustained, reductions in measures of pain, pain-related disability</p>